Hepato-Pancreato-Biliary (HPB) Cancers
What Are HPB Cancers?
Hepato-Pancreato-Biliary (HPB) cancers affect the liver, pancreas, and biliary system (gallbladder and bile ducts). These cancers are often aggressive, making early detection and expert treatment crucial for better outcomes.
Types of HPB Cancers
- Liver Cancer (Hepatocellular Carcinoma - HCC) – The most common liver cancer, often linked to hepatitis or cirrhosis.
- Pancreatic Cancer – Affects the pancreas, with adenocarcinoma being the most common type.
- Gallbladder Cancer – A rare but serious cancer that develops in the gallbladder lining.
- Bile Duct Cancer (Cholangiocarcinoma) – Affects the tubes that carry bile from the liver to the intestine.
Symptoms to Watch For
- Persistent abdominal pain
- Jaundice (yellowing of skin and eyes)
- Unexplained weight loss
- Nausea and vomiting
- Loss of appetite
- Dark urine and pale stools
Risk Factors
- Chronic liver disease (Hepatitis B/C, cirrhosis)
- Heavy alcohol consumption
- Smoking and obesity
- Diabetes and pancreatitis
- Gallstones or bile duct inflammation
- Family history of HPB cancers
Diagnosis & Screening
- Imaging Tests (CT, MRI, Ultrasound, PET scan) – To detect tumors and assess cancer spread.
- Blood Tests (Liver Function, Tumor Markers like CA 19-9, AFP) – Helps identify abnormalities.
- Endoscopy & Biopsy – Examines tissues for cancerous cells.
Treatment Options
- Surgery – Removal of tumors or affected organs (liver resection, Whipple procedure).
- Liver Transplant – A curative option for some liver cancer patients.
- Chemotherapy & Targeted Therapy – Helps slow or eliminate cancer growth.
- Radiation Therapy – Precisely targets and destroys cancer cells.
- Immunotherapy – Boosts the body’s natural defense against cancer.
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Early diagnosis saves lives.